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dc.contributor.advisorMudrack, Kristen
dc.contributor.authorAnderson, Cassidy
dc.date.accessioned2019-04-30T19:33:28Z
dc.date.available2019-04-30T19:33:28Z
dc.date.issued2019-04-30
dc.identifier.urihttp://hdl.handle.net/11558/4294
dc.description.abstractMany neurodegenerative diseases are characterized by mitochondrial dysfunction and oxidative stress, both of which lead to an interconnecting vicious cycle of cell death. Research has indicated that heavy metals found in the modern environment such as aluminum sparks some of the oxidative stress found in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Other research as well as mainstream health medias postulate coconut oil as not only a preventive measure but a potential means to reduce symptoms for Alzheimer’s due to its antioxidant activity. Using yeast as the eukaryotic cell model, mitochondrial dysfunction was measured as a result of aluminum and other metals to induce oxidative stress. After mitochondrial dysfunction and oxidative stress via metals were demonstrated, the yeast was treated with coconut oil before and/or after oxidative stress to determine the ameliorating effects of this particular medium chain triglyceride. Oxidative stress was assessed via fluorochromes in order to determine the oxidative stress. Spectroscopy was utilized to determine mitochondrial activity. Coconut oil is expected to prevent and protect yeast from reactive oxygen species.en_US
dc.language.isoen_USen_US
dc.subjectOxidative stressen_US
dc.subjectParkinson's Diseaseen_US
dc.subjectAlzheimer's Diseaseen_US
dc.subjectCoconut oilen_US
dc.subjectAntioxidanten_US
dc.subjectYeasten_US
dc.subjectMitochondriaen_US
dc.subjectMitochondrial dysfunctionen_US
dc.subjectApoptosisen_US
dc.subjectMedium chain triglycerides (MCTs)en_US
dc.subjectMetal toxicityen_US
dc.subjectRISE Above Research Conference
dc.titleAmeliorating Effects of Virgin Coconut Oil Against Oxidative Stressen_US
dc.typeWorking Paperen_US


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